Can the identification of high risk groups increase the effectiveness of colon cancer screening programmes?
High risk groups of colorectal cancer in Holland make up approximately 20 % of all CRC cases. Since 1980 national registers of patients with inherited CRC have been established in most European countries. The life time risk of developing CRC in familial CRC is circa 20 % in contrast to European individuals with an average risk of 5 %. Surveillance of high-risk groups is attractive because the compliance is high. The best way to identify inherited CRC is to obtain a family history on cancer. Physicians should be educated about the importance of obtaining a family history.