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Which colon cancer screening programmes can we afford? A cost-benefit analysis of different approaches




Health impacts and cost effectiveness associated with screening methods depend on several variables: direct cost of the program, diagnostic and therapeutic efficacy of the method, population compliance, cost savings as a result of disease prevention and finally target population and screening algorithm. - It is important to notice that adenoma recurrence rates after polypectomy suggest that a large population of adenomas may concentrate in a small fraction of the population. A more focused follow-up of positive cases will offer maximum prevention for limited costs.   



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Ernst J. Kuipers